Disease Type:
Ankylosing spondylitis

Description:
Ankylosing spondylitis (AS) is a type of inflammatory arthritis that primarily affects the spine or back. In AS, the joints and ligaments along the spine become inflamed. The inflammation produces pain and stiffness that usually begins in the lower back or buttocks, and may progress into the upper spine, chest and neck. Over time, the joints and bones (vertebrae) may grow together (fuse), causing the spine to become rigid and inflexible. Other joints, such as the hips, shoulders and knees may also be affected. AS is a systemic disease, which means it may affect organs.

Symptoms:
  • Chronic pain and stiffness in the lower back, buttocks and hips (usually develops slowly over several weeks or months).
  • Pain and stiffness that worsens during periods of rest or inactivity and improves with movement and exercise
  • Back pain during the night or early morning
  • Feeling very stiff in the morning

Disease Type:
Back pain

Description:
Many forms of arthritis and related conditions that affect the joints, muscles and/or bones can cause problems like pain, stiffness and swelling in the back. While any part of the back can be affected, the lower back is the most common site of arthritis back pain, most likely because it bears more of the body's weight. Some people also may have back pain that arises from inflammation in the soft tissues in the back and not the spine itself. Others may experience back pain because the sciatic nerve ? which runs through the buttocks ? is inflamed causing hip and back pain.

Symptoms:
  • Pain that doesn?t improve when you lie on your back
  • Weakness, pain or numbness in one or both legs
  • Fever or unintentional weight loss
  • Pain or difficulty when urinating

Disease Type:
Infectious Arthritis

Description:
Infectious arthritis is a form of arthritis caused by an infection in the joint. It is also called septic arthritis. Most types of infectious arthritis are caused by bacteria. The most common of these is Staphylococcus aureus (staph), a bacterium that lives on even healthy skin. Infectious arthritis can also be caused by viral or fungal infections. In most cases, infectious arthritis develops when an infection somewhere else in the body travels through the bloodstream to the joint. Less commonly the infection enters the joint directly through a puncture wound or surgery on or near the joint.

Symptoms:
  • The most common symptoms of infectious arthritis are intense swelling and pain, usually in a single joint.
  • In about half of all cases, infectious arthritis involves the knee, but hips, ankles and wrists are also commonly affected.
  • Less commonly, infectious arthritis affects more than one joint.

Disease Type:
Inflammatory Arthritis

Description:
Inflammatory arthritis is a group of diseases characterized by inflammation of the joints and often other tissues. Many inflammatory forms of arthritis are autoimmune diseases. In autoimmune diseases, the immune system turns against the body it's designed to protect for unknown reasons. Research suggests that for many forms, genetics plays an important role, but it also shows that genes alone do not determine who gets the diseases and that other factors play a role. These factors are likely different for different diseases but may include infectious agents, stress, cigarette smoke and hormones.

Symptoms:
  • Inflammatory arthritis is characterized by pain, swelling, warmth and tenderness in the joints as well as morning stiffness that lasts for more than an hour.
  • Most inflammatory forms of arthritis are systemic (meaning they affect the entire body), other symptoms related to inflammation may occur in other parts of the body.
  • Depending on the specific form of arthritis, these symptoms could include skin rashes, eye inflammation, hair loss, dry mouth and fever.

Disease Type:
Juvenile Idiopathic Arthritis

Description:
Juvenile idiopathic arthritis (JIA) is the most common type of arthritis in children where the immune system mistakenly attacks the body's tissues, causing inflammation in joints and potentially other areas of the body. Juvenile idiopathic arthritis (JIA) is the most common type of arthritis in children. The term idiopathic means "of unknown origin." There are six JIA subtypes. Systemic JIA is considered an autoinflammatory disease. The other types are considered autoimmune diseases. A healthy immune system fights invaders, such as viruses and bacteria. In people with autoimmune or inflammatory diseases, the immune system doesn't work properly. It becomes overactive even when there is no infection to fight, or it mistakenly attacks healthy cells and tissues.
  • Types of JIA
  • Systemic JIA, Oligoarticular JIA , Polyarticular JIA , Juvenile psoriatic arthritis , Enthesitis-related JIA , Undifferentiated arthritis

Symptoms:
  • Joints that are warm to the touch
  • Swelling and tenderness at joints
  • Fever
  • Rash
  • Favoring one limb over another or limping
  • Pain (often worse following sleep or inactivity)
  • Stiffness, especially upon waking in the morning
  • Inability to bend or straighten joints completely
  • Inability to bend or straighten joints completely
  • Fatigue
  • Sleep problems
  • Sleep problems
  • Reduced appetite and/or weight loss